2-Amino-5-bromo-3-methoxybenzoic acid - Names and Identifiers
2-Amino-5-bromo-3-methoxybenzoic acid - Physico-chemical Properties
Molecular Formula | C8H8BrNO3
|
Molar Mass | 246.06 |
Density | 1.703±0.06 g/cm3(Predicted) |
Boling Point | 356.0±42.0 °C(Predicted) |
pKa | 4.43±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
2-Amino-5-bromo-3-methoxybenzoic acid - Introduction
Acid is an organic compound with the chemical formula C9H8BrNO3.
Nature:
-Appearance: Colorless or light yellow crystalline solid;
-Melting point: 173-175 degrees Celsius;
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane.
Use:
-It is a commonly used organic synthesis intermediate that can be used to synthesize other compounds;
-In the field of medicine, it can be used to synthesize the background and participate in the synthesis process of drugs.
Preparation Method:
The acid can be synthesized by the following steps:
1. First, the benzoic acid and sodium nitrite are reacted to obtain 2-nitrobenzoic acid;
2. then, on the basis of nitrobenzoic acid, the nitro group is reduced to amino group by reduction reaction to obtain 2-aminobenzoic acid;
3. Finally, 2-aminobenzoic acid is reacted with bromoformic acid to introduce bromine and methoxy groups to obtain fluoracid.
Safety Information:
-the acid may be irritating to the eyes, skin and respiratory tract, and protective measures should be paid attention to when contacting;
-During use, pay attention to avoid inhaling dust and contact with skin;
-Storage should be sealed and kept away from fire and oxidizing agents.
Last Update:2024-04-09 21:01:54